Allergy & Cold: Dosing, Uses, Side Effects, Interactions, Patient Handouts, Pricing and more from Medscape Reference Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes.It may be used as a nasal/sinus decongestant, as a stimulant, or as a wakefulness-promoting agent in higher doses. It was first characterized in 1889, by the German chemists Ladenburg and Oelschlägel, who used a sample that had been isolated from Ephedra vulgaris by the Merck pharmaceutical. ECHA InfoCard: 100.024.622: Chemical and physical data; Formula: C 20 H 24 N 2: Molar mass: 292.426 g·mol −1: 3D model () Pseudoephedrine 4. Doxylamine 5. Chlorpheniramine 6. Triprolidine 7. Diphenhydramine pH 7 30% 20 mM Na 2HPO 4 70% MeOH pH 11 30% 20 mM TEA 70% MeOH tR = 8.5 tR = 11.4 Page 20 0.0 2.5 5.0 2 4 1 3 Time (min) 2 4 1 3 0.0 2.5 5.0 Time (min) 2 1 4 3 Time (min) Peak Tailing - Column Contamination Column: StableBond SB-C8, 4.6 x 250 mm, 5μm Mobile Phase: 20% H 2O : 80% MeOH Flow Rate: 1.0 mL/min. Triprolidine side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using triprolidine and call your doctor at once if you have: painful or difficult urination.